Ilungele ntoni ipqq?

I-PQQ (pyrroloquinoline quinone) idla ngokubizwa ngokuba yivithamini yokuphila ixesha elide. Kwaye esi siqhulo sinezizathu ezivakalayo emva kwayo. I-PQQ inokunceda ukuphucula ukugxila kwengqondo, ukonyusa amandla-kwaye ewe, nokunceda ukuba uphile ixesha elide! Ke, iyenza njani le nto iPQQ? Ivela phi? Ngaba kufuneka uqale ukubandakanya esi songezo kulawulo lwakho lwesiqhelo? Makhe sifumanise. 

Yintoni i-PQQ? 

PQQ, imfutshane yePyrroloquinoline quinone, yinto entsha efunyenweyo njengenye yezona khemikhali zinamandla emhlabeni, kunye nobuninzi obumangalisayo beenzuzo zempilo ezinokubakho. Ukusukela oko yafunyanwa, iye yatsala ingqalelo enkulu kwiipropathi ezingaqhelekanga ze-antioxidant ezizisa ekwandiseni amandla eselula ngokuxhasa umsebenzi we-mitochondrial eyona "injini" yeeseli zethu.

Le khompawundi ayigcini nje ukusindisa iiseli kumonakalo owenziwe nge-oxidative kodwa ikwakhuthaza ukuveliswa kwe-mitochondria entsha. Ngoko ke kubaluleke kakhulu ukugcina amandla ekwinqanaba elifanelekileyo, ukuphepha ukudinwa, kunye nokugcina amandla ngokubanzi. Uphando luthi i-PQQ ineempembelelo ezixhasayo ekukhuthazeni ukusebenza kwengqondo kunye nokuphucula inkxaso kwimpilo yobuchopho kunye nenkumbulo eneempawu zokukhusela i-neuroprotection. Amandla ayo okukhuthaza impilo yentliziyo, ukunciphisa ukudumba, kunye nokukhuthaza ukwaluphala okunempilo kwenza ukuba ibe sisongezelelo esimnandi sempilo yexesha elide. Ngesi senzo sahlukeneyo, i-PQQ ijongwa njengemodyuli ekugcineni impilo yeselula, ukuthintela ukwehla okunxulumene neminyaka yobudala, kunye nokuphucula imetabolism yamandla-yiyo ke isango lempilo engcono.

I-PQQ yikhompawundi efana neevithamini ezifumaneka kwikiwis, isipinatshi, iimbotyi zesoya, ubisi lwebele lomntu, kunye nomhlaba. Ngokwenene iveliswa ziintsholongwane. Ngapha koko, ngaphakathi kweebhaktheriya, i-PQQ inceda ukophula utywala kunye neswekile kwaye iziguqule zibe ngamandla. Izityalo ezininzi ziphela zine-PQQ ekufunxeni kwayo ngokudlula emhlabeni. ​​​​​​​

 

 

Ukuqonda i-PQQ: Ukuntywila ngokuNzulu kwiMvelaphi kunye neePropati zayo

I-PQQ, i-Pyrroloquinoline quinone, Yikhompawundi engaqhelekanga ethe mva nje ibe sembindini wengxoxo-mpikiswano enkulu kwindima yayo enokubakho njenge-antioxidant eyomeleleyo kunye ne-arhente yempilo yeselula. Nangona okokuqala yafunyanwa njengebhaktheriya ekwanti, apho isebenza njenge-cofactor ye-enzyme-catalyzed reaction, i-PQQ sele ifunyenwe kweminye imithombo yokutya kunye nomzimba womntu. I-PQQ ineenzuzo ezahlukeneyo zempilo ezibandakanya:

I-PQQ, okanye i-Pyrroloquinoline Quinone, yenye yezondlo eziphambili ezisetyenziselwa ukukhuthaza amandla eseli kunye nokuthintela uxinzelelo lwe-oxidative. Le khompawundi ibalulekile kwimpilo jikelele kunye nokuba sempilweni kwaye inika izibonelelo ezininzi kwiinkqubo ezahlukeneyo zomzimba.

• Yongeza umsebenzi we-mitochondrial: Ivuselela uphuhliso kunye nomsebenzi we-mitochondria, indlu yamandla yeeseli, ukuzisa ukomelela kumanqanaba amandla kunye nokudinwa okuncinci.

• Isebenza njenge-antioxidant eyomeleleyo: Inciphisa ii-radicals zasimahla eziza kuthatha i-oxidation kwiiseli, ngenxa yoko ibambezela inkqubo yokuguga.

• Inceda kwimisebenzi yengqondo: Iphakamisa ukukhula kwee-neurons kunye neeseli ze-nerve ezikhokelela kwimemori engcono, ukufunda, kunye nempilo yengqondo.

• Ukuphucula impilo ye-cardiovascular: Yehlisa ukudumba kunye ne-cholesterol embi (LDL) ngaloo ndlela inceda ukusebenza kwentliziyo ngelixa inciphisa ukubakho kwesifo sentliziyo.

• Yandisa ukhuseleko: Yehlisa uxinzelelo lwe-oxidative kunye nokudumba ngaloo ndlela iphucula imisebenzi yomzimba yokulwa nosulelo kunye nokugcina umzimba usempilweni entle.

 

 

I-PQQ vs. Ezinye ii-Antioxidants: Ukuthelekisa iiNzuzo kwiMpilo yakho

I-Pyrroloquinoline Quinone, efinyeziweyo kwi-PQQ, yi-antioxidant eneempawu zayo ezininzi, ezahlukileyo kwaye zodwa. Naku ukucalulwa kwezibonelelo phakathi kwe-PQQ kunye nezinye i-antioxidants kwimpilo yakho:

umba	I-PQQ (i-Pyrrolo-quinoline Quinone)	Vitamin C	Vitamin E	I-CoQ10 (Coenzyme Q10)
Umsebenzi wasePrayimari	I-biogenesis ye-Mitochondrial, amandla eselula, ukhuseleko lwe-neuro	Ukuxhaswa kwamajoni omzimba, ukuveliswa kwe-collagen	Ikhusela inwebu zeseli, ulusu kunye nempilo yamehlo	Ixhasa impilo yentliziyo, amandla eselula
Uhlobo lwe-Antioxidant	I-antioxidant enamandla, ihlala ixesha elide	I-antioxidant enyibilikayo emanzini	I-antioxidant enyibilikayo ngamanqatha	I-antioxidant enyibilikayo ngamanqatha
Inkxaso yeMitochondrial	Yenza i-mitochondria entsha, iphucula amandla	Akukho ncedo lwemitochondrial ngqo	Akukho ncedo lwemitochondrial ngqo	Ukuphucula ukusebenza kakuhle kwe-mitochondrial
Iinzuzo zengqondo	Ikhuthaza ukukhula kwe-neuron, ikhusela impilo yengqondo	Inkxaso encinci yengqondo	Inkxaso yengqondo encinci	Inkxaso yengqondo encinci
Heart Health	Iyanciphisa uxinzelelo lwe-oxidative, ixhasa iiseli zentliziyo	Iinzuzo zempilo yentliziyo encinci	Ikhusela imithambo yegazi, inciphisa ukuvuvukala	Ikhusela iiseli zentliziyo, iphucula ukuhamba kwegazi
Inkqubo yomzimba	Ukunciphisa uxinzelelo lwe-oxidative, ukuxhaswa kwe-immune yesibini	I-immune booster eyomeleleyo	Inkxaso yomzimba ephakathi	Inkxaso yomzimba ephakathi
Impilo Yesikhumba	Ukhuseleko oluqhelekileyo lwe-antioxidant	Khuthaza collagen, ixhasa ukuphiliswa kwesikhumba	Ikhusela iiseli zolusu kumonakalo	Izibonelelo ezilinganiselweyo zolusu
Ubude beempembelelo	Iziphumo ezihlala ixesha elide	Ixesha elifutshane, lifuna ukuphinda lizaliswe rhoqo	Ixesha eliphakathi kwimimandla ye-lipid	Iziphumo eziphakathi kwexesha elide
Iipropati ezichasene nokuguga	Inciphisa uxinzelelo lwe-oxidative, ikhuthaza impilo yeselula	Ixhasa i-collagen kwisikhumba solutsha	Inciphisa ukuguga kwesikhumba, ikhusela iimbumba zeeseli	Ikhusela i-mitochondria kumonakalo wokuguga
Eyona ilungiselelwe	Ukuphucula amandla eselula, impilo yengqondo, ubomi obude	Ukwandisa ukukhuseleka, ukuphulukiswa kwesikhumba	Ulusu, impilo yamehlo, i-anti-inflammation	Impilo yentliziyo, ukusebenza kakuhle kwe-mitochondrial
Umthamo oqhelekileyo	I-10-20 mg / ngosuku	I-500-1000 mg / ngosuku	I-15-30 mg / ngosuku	I-100-200 mg / ngosuku

Zonke ii-antioxidants zizisa izibonelelo ezininzi emzimbeni wakho, ukanti i-PQQ yahluke kakhulu ngenxa yendima yayo ekwandiseni ukusebenza kwe-mitochondria, igalelo kwimpilo yobuchopho, kunye nokubonelela ngokhuseleko lwexesha elide kumonakalo owenziwe nge-oxidative. Ukuba ufuna ukonyusa amandla kwiiseli kunye nobuchule bokuqonda, i-PQQ inokuba lolona khetho lungcono kuwe.

 

Impilo yolusu: Ngaba i-PQQ ingakuphucula ukuntsonkotha kwakho kunye nokunciphisa ukuguga?

I-PQQ (Pyrroloquinoline Quinone) ineendlela ezininzi zokuphucula ibala lakho kunye nokunciphisa ukuguga: inokulungisa amandla eseli, incede kwimpilo yobuchopho kwaye ibe nefuthe elihle eluswini ngentaphane yayo yokuchasa ukuguga kunye nokuchasana nemibimbi:

• Yehlisa Uxinzelelo lweOxidative: I-PQQ yi-antioxidant enamandla kakhulu ekhupha umzimba kwiiradicals zasimahla, ikhusela ulusu kumonakalo we-oxidative kunye nokuthintela imibimbi kunye nokuba buthuntu.

• Ikhuthaza ukwanda kwe-collagen, kwaye igcina amanqanaba ee-tissue, ngaloo ndlela inika ulusu oluqinileyo kunye olulula.

• Ukwandisa amandla eSelula: I-PQQ iphucula imisebenzi ye-mitochondrial enceda ekulungisweni kweeseli kunye nokuhlaziywa ngokutsha ngokuyinika inkangeleko encinci.

• I-Antioxidant / anti-inflammatory: Ke ngoko, oku kuphelisa ukucaphuka kunye nobubomvu obuphuma ekugugeni.

• Ukonakala kwendalo: Le nto ikhusela ulusu ekonakalisweni Imitha ye-UV kunye nongcoliso, ngaloo ndlela igcina ubutsha bayo njengoko bufanele.

I-antioxidant, i-anti-inflammatory kunye ne-mitochondrial-enhancing properties ye-PQQ kufuneka incede ukuphucula impilo yolusu ngokusebenzisa iziphumo ezikhuselayo kuxinzelelo lwe-oxidative, ukunyuka kwemveliso ye-collagen, ukuvutha okuncinci, kunye nokulungiswa kweeseli. Ngelixa uphando oluninzi kufuneka lwenziwe ukumisela inzuzo yalo eluswini, ezi nyaniso malunga ne-PQQ ngenene ziindlela ezithembisayo zokuphucula ibala kunye nobumnyama.

 

​​​​​​​

Umsebenzi Wengqondo: Ukuphonononga iiNzuzo zoQoqosho lwePQQ​​​​​​​​​​​​​​

Iprroloquinoline quinone (PQQ) iye yafumana umdla ngakumbi malunga neenzuzo kwiinzuzo zengqondo, ngenxa yeempawu zayo zokuphucula i-neuroprotective kunye ne-mitochondrial. Oku kulandelayo kuchaza indlela i-PQQ exhasa ngayo ukusebenza kwengqondo kunye nokuba sempilweni kwengqondo:

• Neuroprotection: I-PQQ ineepropathi ezinamandla kakhulu ze-antioxidant ezisetyenziselwa ukukhusela iiseli ze-neuron kwingqondo kuxinzelelo lwe-oxidative, ebandakanyeka kakhulu kwizifo ze-neurodeergenerative ze-Alzheimer's kunye ne-Parkinson.
• I-Mitochondrial Biogenesis: I-PQQ ivuselela ukuveliswa kwe-mitochondria entsha ngaphakathi kweeseli zobuchopho. Kuba amandla aveliswa ngaphakathi kwe-mitochondria, ukwanda kwamanani kuya kuphucula ukusebenza kwengqondo. Oku kuya kuphucula ukucaca kwengqondo kunye nengqalelo, ngaloo ndlela iphucula imetabolism yamandla ngaphakathi kwengqondo.
• I-Neurogenesis: I-PQQ ivuselela ukuveliswa kwe-NGF, eyenza ukukhula, ukutya kunye nokusinda kwee-neurons. Yiyo loo nto ikhuthaza ubuchopho beplastiki ngokubanzi, ngeenjongo zokufunda kunye nokwenza inkumbulo.
• Iziphumo zokuchasa ukudumba: Ukudumba okungapheliyo kwengqondo kuye kwadityaniswa nokungasebenzi kakuhle kwengqondo. Ukuthintelwa kweenkqubo ezinxulumene nokudumba kunokuthintela ukuqhubeka kwezifo ze-neurodeergenerative kunye nokulahleka kwenkumbulo okunxulumene neminyaka.
• Umsebenzi wokuqonda kunye nenkumbulo: Ukongezwa nge-PQQ kubonakaliswe ukuphucula inkumbulo, ingqalelo, kunye nomsebenzi olawulayo kwizifundo zeklinikhi zombini kubathathi-nxaxheba abasempilweni kunye nabo banokukhubazeka kwengqondo.

Ukunika izibonelelo ezinje ngokuphucula amandla engqondo, ukhuseleko lwe-neuron, kunye nenkxaso yemisebenzi yokuqonda, ukubakho kwe-PQQ ekuphuculeni inkumbulo, ukugxila, kunye nempilo yengqondo, ngokubanzi, iyathembisa njengearhente eyongeza.

 

 

isiphelo

Iprroloquinoline quinone (PQQ) ingaphezulu nje kwesondlo-yikhompawundi enamandla eneziphumo ezinzulu kumandla eselula, impilo ye-mitochondrial, kunye nokuphila kakuhle. Ukusuka ekomelezeni ukusebenza kwengqondo kunye nokuxhasa inkumbulo ukunyusa imveliso yamandla, ukuphucula impilo yentliziyo, kunye nokusebenza njenge-antioxidant eyomeleleyo, i-PQQ ibonisa isithembiso njengesongezelelo esisebenzayo. Ngelixa izifundo zeklinikhi zexesha elide zifuneka, ubungqina obukhoyo bubonisa indima enokubakho ekukhuthazeni ukuguga okunempilo, ukukhusela kuxinzelelo lwe-oxidative, kunye nokuxhasa amandla okuqonda.

Kwabo bafuna ukuxhasa ngokwendalo ukuxhasa imetabolism yamandla, ukusebenza kwengqondo, kunye nempilo yeselula yexesha elide, ukuxhaswa kwe-PQQ kunokuba lulongezelelo oluxabisekileyo kwindlela yokuphila kakuhle. Nangona kunjalo, njengazo zonke izongezo zokutya, kungcono ukudibana nengcali yezempilo ngaphambi kokuba uqalise, ngakumbi kubantu abaneemeko zonyango okanye abakhulelweyo okanye abancancisayo.

Ungathenga Umgubo wePQQ kwinkampani ye-yanggebiotech ngumenzi okhokelayo kwishishini kunye nosasazo lwezongezo zokutya ezisulungekileyo. yanggebiotech.com ayilophawu lwabathengi nje. Ikwabonelela ngezithako ezicocekileyo kwezinye iibrendi ezihambisa ukutya kunye nezinye iimveliso ezongezelelweyo. Qhagamshelana yangebiotech.com ukwenza iodolo namhlanje.

Ucaphulo

1. Jonscher KR, et al. Ukongezwa kwangethuba kwe-PQQ kuneziphumo eziqhubekayo zokukhusela ixesha elide kwinkqubo yophuhliso lwe-hepatic lipotoxicity kunye nokudumba kwiimpuku ezityebileyo. I-FASEB J. 2017 Epreli; 31 (4): 1434-1448.
2. Harris CB, et al. I-Dietary pyrroloquinoline quinone (PQQ) iguqula izikhombisi zokuvuvukala kunye ne-metabolism enxulumene ne-mitochondrial kwizifundo zabantu. J Nutr Biochem. 2013 Dec;24(12):2076-2084.
3. Brand MD, et al. Indima yomsebenzi we-mitochondrial kunye ne-bioenergetics yeselula ekugugeni kunye nezifo. UBr J Dermatol. 2013 Jul;169(Supp 2):1-8.
4. UMecocci P, kunye no-al. Umonakalo we-oxidative kwi-DNA ye-mitochondrial ibonisa ukunyuka okuxhomekeke kwiminyaka yobudala kwingqondo yomntu. Ann Neurol. 1993 Okt;34(4):609-616.
5. UAizenman E, et al. Ukusebenzisana kwesakhamzimba esibalulekileyo se-pyrroloquinoline quinone kunye ne-N-methyl-D-aspartate receptor redox site modulatory. J Neurosci. 1992 Jun;12(6):2362-2369.
6. Bauerly K, et al. Ukutshintsha imeko yesondlo se-pyrroloquinoline quinone kulungelelanisa i-mitochondrial, i-lipid, kunye ne-metabolism yamandla kwiimpuku. I-PLoS enye. 2011;6(7):e21779.
7. Ohwada K, et al. I-Pyrroloquinoline quinone (PQQ) ikhusela ukusilela kwengqondo okubangelwa luxinzelelo lwe-oxidative kwiimpuku. J Clin Biochem Nutr. 2008 Jan;42(1):29-34.
8. UZhang P, kunye nabanye. Ukukhuselwa kwe-pyrroloquinoline quinone ngokuchasene ne-methylmercury-induced neurotoxicity ngokunciphisa uxinzelelo lwe-oxidative. I-Radic Res yasimahla. 2009 Mar;43(3):224-233.
9. UItoh Y, et al. Isiphumo se-antioxidant supplement pyrroloquinoline quinone disodium ityuwa (BioPQQ™) kwimisebenzi yengqondo. Adv Exp Med Biol. 2016;876:319-325.
10. Nakano M, et al. Iziphumo ze-pyrroloquinoline quinone disodium yetyuwa yokuthatha kumanqanaba e-cholesterol e-serum yabantu abadala baseJapan abasempilweni. J Nutr Sci Vitaminol (Tokyo). 2015;61(3):233-240.