Ngaba ndingathatha i-pqq nge-coq10?
Kwibutho labantu lanamhlanje elihamba ngokukhawuleza, impilo iye yaba yeyona nto ibalulekileyo abantu abangenakuyityeshela. Ukuthatha izongezo zokuphucula ukomelela komzimba kunye nokomeleza ukhuselo lomzimba kuye kwaxhaphaka ngakumbi. PQQ kwaye CoQ10, njengezongezelelo ezimbini zamandla kushishino, zihlala zithelekiswa enye kwenye.
Yintoni i-PQQ?
I-PQQ (pyrroloquinoline quinone) yinto efana ne-vitamin eyafunyanwa ngo-1979. Ekubeni umzimba awukwazi ukuvelisa i-PQQ ngokwawo, kukholelwa ukuba inokuba yivithamin entsha. Ekuqaleni kwenkulungwane yama-21, yaqatshelwa njengenxalenye yosapho lwevithamin B.¹
Namhlanje, le nto ithathwa njenge-cofactor kwi-metabolism. I-PQQ ibandakanyeka kwiimpendulo ezibalulekileyo, ngakumbi kwi-mitochondria. I-PQQ ikwayinto ebizwa ngokuba yi-coenzyme emzimbeni.
Yintoni i-coenzyme?
Igama elithile coenzyme kuthetha ukuba umzimba usebenzisa le nto ukusabela kwimetabolism kwaye uyisebenzise kwinkqubo. Impendulo ayinakwenzeka ngaphandle kwe-coenzyme. Iyingxenye ye-enzyme kunye noncedo olubalulekileyo kwiinkqubo ngaphakathi kwezinto eziphilayo.
Impembelelo ye-PQQ: Yintoni eyenziwa yi-coenzyme kumzimba wakho?
Sele kukho ngaphezu kwe-1,100 amangeno malunga PQQ kwi-Pubmed, elinye lamaqonga amakhulu ophando amayeza. Ungeniso oludumileyo lokukhangela lubandakanya "i-PQQ kunye ne-mitochondria" kunye ne "PQQ kunye nokuvutha".
Ukukunceda ufumane umbono wesiphumo se-PQQ, sidibanise ezinye ze iimpawu ezibalulekileyo kuwe - kubandakanywa nemithombo ukuze ukwazi ukufunda iinyani ngokwakho ngexesha lakho lokuphumla:
Yomeleza imitochondria : I-PQQ inokuqinisekisa ukuba i-mitochondria iyakhula kwiiseli zomzimba kwaye ngaloo ndlela ixhasa imveliso yamandla
Ukuphelisa ukudumba: I-PQQ inokukhuthaza ukuveliswa kwezithunywa ezichasene nokudumba kwaye ngaloo ndlela ibe negalelo kummiselo wokudumba²
Ukuxhasa ikhonkco lokuphefumla: I-PQQ idlala indima kwimetabolism yamandla
Ukuguga ngcono: I-PQQ inokunciphisa uxinzelelo lwe-oxidative kwaye ngaloo ndlela ihambe kunye nenkqubo yokuguga
Nika amandla: I-PQQ inokuhlaziya i-coenzyme Q10 ukuze iqhubeke nokusebenza kwimveliso yamandla
Umsebenzi: Yintoni i-coenzyme Q10 enayo kwimpilo yakho?
I-Q10 ifumaneka ngaphakathi kweeseli ikakhulu kwi-mitochondria. Ngokuchanekileyo, i-substance ibekwe kwi-membrane ye-mitochondrial yangaphakathi. Njengamanye amaninzi e-coenzymes, i-ubiquinol ibandakanyeka kwikhonkco lokuphefumla kwaye isebenza njenge-electron carrier.
Ngaphandle kwe-coenzyme Q10, i-mitochondria ayinakukwazi ukwenza umsebenzi wayo kwaye imveliso yamandla eyenzekayo apho inokuma. Oku kungenxa yokuba i-Q10 isekuqaleni kwekhonkco lokudlulisa i-electron. Ukuba kukho iingxaki ngeli nqanaba, izinto azikwazi ukuqhubeka kwaye umzimba awukwazi ukuvelisa amandla aneleyo.
Kanye njenge-PQQ, i-coenzyme ingumncedi obalulekileyo kwi-mitochondria yakho, ukuze babe nokuvelisa amandla kwaye bakunike amandla kwimisebenzi yakho. Ukusilela kwe-coenzyme Q10 kuya kuba nemiphumo yomzimba.
Isetyenziselwa ntoni iPQQ?
PQQ, mfutshane ye Iprroloquinoline Quinone, i-bioactive compound enemisebenzi emininzi yezinto eziphilayo, kwaye ikwabizwa ngokuba yi "vitamin ye-14" kuluntu lwezonyango lwehlabathi. I-PQQ ifumaneka ngokubanzi kwiimicroorganisms, izityalo, izilwanyana, kunye nomzimba womntu, nto leyo eyenza ukuba ibe sisondlo esibalulekileyo. Imisebenzi yayo ingashwankathelwa ngolu hlobo lulandelayo:
| Antioxidant | I-PQQ inokunceda ukuphelisa iiradicals zasimahla emzimbeni ukuya kuthi ga kwinqanaba elithile, isebenze njenge-antioxidant kunye nokukhusela amalungu anjengentliziyo kunye nesibindi kumonakalo owenziwe nge-oxidative. |
| Ukukhuselwa kweNerve | I-PQQ inokukhusela inkqubo yemithambo-luvo kwaye ihlala isebenza kakuhle ekunyangeni iimpawu ezibangelwa kukudinwa kwengqondo, njengokuphuthelwa kunye namaphupha acacileyo. |
| Ukuphucula iMemori | I-PQQ inokuphucula umonakalo we-neuronal obangelwa kukunqongophala kweglucose, ngaloo ndlela iphucula ukusebenza kwememori. |
| I-Immunity eyongeziweyo | I-PQQ ivuselela ukusebenza kunye nokwanda kweeseli zomzimba, ngaloo ndlela iphucula amajoni omzimba kunye nokwandisa ukuxhathisa izifo. |
| Ukomelezwa kweMetabolism | I-PQQ inyusa imetabolism ukuya kuthi ga kwinqanaba elithile, iphucula amandla omzimba wemetabolism kwaye inceda ekupheliseni i-toxins emzimbeni. |
Isetyenziselwa ntoni iCoQ10?
I-CoQ10, okanye i-coenzyme Q10, yikhompawundi ye-quinone enyibilikayo efumaneka ngokubanzi kwizinto eziphilayo. Ifumaneka ngokuyinhloko kwi-membrane yangaphakathi ye-mitochondria kwaye i-lipid-soluble compound efana nesakhiwo kwi-vitamin K. Imisebenzi yayo inokushwankathelwa ngolu hlobo lulandelayo:
| Ixhasa iMpilo yeNtliziyo | I-CoQ10 yinxalenye ebalulekileyo yemveliso yamandla ngaphakathi kweeseli zentliziyo. Inceda ukuphucula ukunyanzeliswa kwentliziyo kunye nemveliso, yehlisa uxinzelelo lwegazi, kwaye ikhusela intliziyo kumonakalo woxinzelelo lwe-oxidative. |
| Antioxidant | I-CoQ10 ineepropathi ezinamandla ze-antioxidant, ezikwazi ukukhupha i-oxygen free radicals kunye nokunciphisa umonakalo owenziwe kwi-oxidative kwiiseli. Oku kunceda ukucotha inkqubo yokuguga kunye nokuthintela ukuqala kwezifo ezahlukahlukeneyo ezingapheliyo. |
| Uphucula uMzimba wokuSebenza | I-CoQ10 yandisa imveliso ye-ATP ngaphakathi kweeseli, inika amandla amaninzi okusebenza ngokomzimba, ngaloo ndlela iphucula ukunyamezela kunye nokusebenza kwezemidlalo. |
| Ikhuthaza iMpilo yeZihlunu | I-CoQ10 inceda ukunciphisa umonakalo wemisipha kunye nexesha lokubuyisela, iphakamisa amandla emisipha, kwaye ibaluleke kakhulu kubantu abenza imisebenzi ephezulu yomzimba. |
| Uphucula umsebenzi weCognitive | I-CoQ10 inokuba luncedo ekwandiseni umsebenzi wokuqonda, kubandakanya inkumbulo kunye nengqalelo. Kubaluleke kakhulu kuthintelo kunye nonyango lwezifo ze-neurodeergenerative ezifana ne-Alzheimer's kunye ne-Parkinson's. |
Isebenza njani i-CoQ10 kunye ne-PQQ?
Ukuba i-CoQ10 isebenza ukuphucula isantya kunye nokusebenza kakuhle, ngoko i-PQQ inceda ngokukhuthaza ukukhula kwe-mitochrondria kwaye kunye bancedisa umzimba wakho ukuvelisa amandla amaninzi, ngokukhawuleza. Cinga ngenkqubo yokuvelisa amandla eselula njengololiwe.
1) Uloliwe ukwindawo yakhe yokuqala kwaye ugcwele ukutya kunye neoksijini.
2) Uloliwe uthunyelwa kwindawo yakhe yokugqibela apho umzimba wakho uya kuthatha ukutya kunye neoksijini, kwaye uyiguqule ibe amandla.
3) Uloliwe ubuyela kwindawo awayekuyo ngamandla apho umzimba wakho uza kusebenzisa, kwaye endaweni yawo ukutya okuninzi kunye neoksijini. Inkqubo ke iphinda.
Kulo mzekelo, uloliwe yi-mitochondria yakho okanye izindlu zamandla ezinoxanduva lwenkqubo yokuguqula ukutya kunye neoksijini zibe amandla e-ATP. I-CoQ10 ifana ne-supercharger ephucula isantya sikaloliwe. I-PQQ ifana nenkampani yokwakha ehlala isebenzela ukongeza iimoto ezongezelelweyo kuloliwe wakho. Ngamafutshane, i-CoQ10 iphucula isantya sikaloliwe wakho wokuvelisa amandla, ngelixa i-PQQ isongeza kwaye isakha umthamo owongezelelweyo kuloliwe wakho.
Ngokudibeneyo banikezela ngenqindi enye-ezimbini ekwandiseni imveliso yamandla eselula. Ngelixa uphando olongezelelweyo kufuneka luqhutywe kwiziphumo ze-CoQ10 kunye ne-PQQ ezithathwe kunye, izifundo eziqhutywe ngokwahlukeneyo kwisongezo ngasinye zibonisa ukuba zombini zineenzuzo ezahlukileyo kwimveliso yamandla eselula, impilo yentliziyo kunye nempilo yengqondo.
Kutheni ndidinga zombini i-PQQ kunye ne-CoQ10?
PQQ i-nootropic exhasa imemori, inika amandla, ikhusela ingqondo kunye nokuncedisa i-mitochondria ngokwandisa amanani abo. I-CoQ10 iqinisekisa ukuba imitochondria onayo isebenza ngokusemandleni abo. Ukuba unemitochondria eninzi isebenza “ngentlantsi” eninzi, unokuba namandla amaninzi, iiseli ezisempilweni, kunye nokuphucula ukusebenza kwengqondo kunye nomzimba.
Zombini i-PQQ kunye ne-CoQ10 zinxulumene ne-mitochondria, ngaba azenzi into enye? Hayi, i-CoQ10 kunye ne-PQQ azifani. Kunoko, bayaxhasana yaye bayakhuthazana. Bazenza ngcono omnye komnye. Bebonke babonelela ngenzuzo enkulu kunokuba ithathwe ngabanye. Kukho isiphumo sokuphindaphinda ukudibanisa ezi nootropics zimbini ezinamandla.
isiphelo
Ukudibana CoQ10 kwaye PQQ inikeza isixhobo esinamandla sokuphucula imveliso yamandla, ukuxhasa impilo ye-cardiovascular, ukunyusa umsebenzi wokuqonda, kunye nokukhuthaza ubomi obude. Ngokukhusela iiseli kumonakalo we-oxidative kunye nokuxhasa ukusebenza kwe-mitochondrial, ezi zondlo zinceda ukugcina impilo yonke yeselula, ebaluleke kakhulu ekugugeni ngobubele kunye nokugcina indlela yokuphila esebenzayo.
Kwabo bajonge ukonyusa ukutya kwabo okunesondlo, ukuthathela ingqalelo izongezo ezidibanisa i-CoQ10 kunye ne-PQQ zinokuba luncedo kwirejimeni yezempilo.
Ucaphulo
deutsche-apotheker-zeitung.de/daz-az/2003/daz-19-2003/uid-9706
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