I-Resveratrol: I-Antioxidant ekufuneka Uyazi Ngayo

I-Resveratrol ilwa njani nokuguga kwaye iphucula impilo

Ibango le-Resveratrol lodumo lilele kwiipropathi zayo ezinamandla ze-antioxidant. Njengoko sikhula, imizimba yethu iqokelela umonakalo ovela kwiiradicals zasimahla - iimolekyuli ezingazinzanga ezinokwenzakalisa iiseli zethu. Olu xinzelelo lwe-oxidative lunegalelo kwinkqubo yokuguga kunye nemiba eyahlukeneyo yempilo. Faka i-resveratrol, ikhompawundi elwa nezi radicals zasimahla kwaye inceda ukukhusela iiseli zethu emonakalweni.

Enye yezona zinto zinomdla kakhulu ze-resveratrol kukukwazi ukwenza i-sirtuins isebenze, edla ngokubizwa ngokuba "yimfuza yokuphila ixesha elide." Ezi proteni zidlala indima ebalulekileyo ekulawuleni impilo yeselula kunye nobomi. Ngokusebenzisa i-sirtuins, i-resveratrol inokunceda ukunciphisa inkqubo yokuguga kwinqanaba leselula, elinokukhokelela ekuphuculeni impilo kunye nokuphila ixesha elide.

Ngaphandle kwemiphumo yokuguga, i-resveratrol ibonise isithembiso sokuxhasa impilo ye-cardiovascular. Uphononongo lucebisa ukuba kunokunceda ukunciphisa ukuvuvukala, ukuthoba uxinzelelo lwegazi, kunye nokuphucula amanqanaba e-cholesterol. Ezi zibonelelo zinokufaka isandla kwintliziyo esempilweni kwaye zinciphise umngcipheko wezifo zentliziyo.

Impembelelo yeResveratrol kwimpilo yengqondo yenye indawo enomdla. Uphando lubonisa ukuba le khompawundi inokunceda ukukhusela iiseli zengqondo emonakalweni kwaye inciphise umngcipheko wezifo ze-neurodeergenerative ezifana ne-Alzheimer's. Iipropathi zayo ze-neuroprotective zinokuthi ziphucule umsebenzi wokuqonda kunye nenkumbulo njengoko sikhula.

Iimpembelelo zekhompawundi zinabela kwimpilo ye-metabolic ngokunjalo. Olunye uphando lufumene ukuba i-resveratrol inokunceda ukuphucula uvakalelo lwe-insulin kunye ne-glucose metabolism, enokuba luncedo kubantu abanesifo seswekile okanye abasengozini yohlobo lwe-2. Ukongeza, inokunceda ekulawuleni ubunzima ngokuchaphazela i-fat metabolism kunye nokugcinwa.

Izongezo zeResveratrol: Ngaba ziyasebenza ngokwenene?

Ngomdla okhulayo kwizibonelelo zempilo ze-resveratrol, intengiso ibone utyando kwizongezo ze-resveratrol. Kodwa umbuzo usamile: ngaba ezi zongezo ziyazifeza ngokwenene izithembiso zazo?

Ukusebenza kwe-resveratrol supplements sisihloko sengxoxo eqhubekayo kuluntu lwesayensi. Nangona uphando oluninzi lwebhubhoratri kunye nezilwanyana lubonise iziphumo ezithembisayo, izifundo zabantu ziye zavelisa iziphumo ezixubileyo. Omnye umceli mngeni kukuba i-resveratrol ine-bioavailability ephantsi, oku kuthetha ukuba ininzi yayo i-metabolized ngaphambi kokuba isetyenziswe ngumzimba.

Nangona le mingeni, ezinye izifundo zichaze iziphumo ezilungileyo ezivela kwi-resveratrol supplementation. Ngokomzekelo, uphononongo lwezilingo zeklinikhi lufumene ukuba izongezelelo ze-resveratrol zinokunceda ukuphucula imingcipheko yenhliziyo, njengokunciphisa uxinzelelo lwegazi lwe-systolic kunye namanqanaba e-cholesterol epheleleyo. Nangona kunjalo, ababhali baqaphele ukuba uphando olongezelelweyo luyafuneka ukumisela iidosi ezifanelekileyo kunye nemiphumo yexesha elide.

Xa kufikwa kwizibonelelo zokulwa nokuguga, i-jury isaphumile. Nangona ezinye izifundo zibonise ukuphuculwa kwamanqaku okuguga kwamaselula kunye ne-resveratrol supplementation, abanye abafumananga miphumo ebalulekileyo. Kubalulekile ukuqaphela ukuba uninzi lwezi zifundo zisebenzisa iidosi ezahlukeneyo kunye nemixube, nto leyo eyenza kube nzima ukwenza izigqibo eziqinisekileyo.

Ifomu ye-resveratrol esetyenziswa kwizongezo inokuchaphazela ukusebenza kwayo. I-Trans-resveratrol ithathwa njengeyona fom ye-bioavailable, kwaye ezininzi izongezo eziphezulu eziphezulu zisebenzisa olu hlobo. Abanye abavelisi baphinda bajonge iindlela zokuphucula ukufunxa kwe-resveratrol, njengokusebenzisa iinkqubo zokuhanjiswa kwe-liposomal okanye ukudibanisa nezinye iikhompawundi ezinokonyusa ukufumaneka kwayo kwe-bioavailability.

Kuyafaneleka ukuba uqaphele ukuba ngelixa izongezelelo zinokubonelela ngeedosi ezigxininisiweyo ze-resveratrol, zisenokunganikeli ngezibonelelo ezifanayo njengokutya ukutya okutyebileyo kwe-resveratrol. Ukutya okupheleleyo kuqulethe uluhlu olunzima lwezondlo kunye neekhompawundi ezisebenza ngokubambisana, ezinokuthi ziphucule izibonelelo ze-resveratrol.

Uphando lwangoku kwi-Resveratrol kunye noThintelo lweZifo

Amandla e-resveratrol ekuthinteleni izifo aqhubeka nokuba ngumxholo oshushu kuphando lwezenzululwazi. Izifundo ezininzi zivavanya ukuba le khompawundi inokunceda njani kumlo ochasene nezifo ezingapheliyo.

Ukuthintela umhlaza yindawo enye apho i-resveratrol ibonise isithembiso. Izifundo zaselabhoratri zibonise ukuba i-resveratrol inokuthintela ukukhula kweeseli zomhlaza kwaye ibangele i-apoptosis (ukufa kweseli ecwangcisiweyo) kwiindidi ezahlukeneyo zomhlaza, kubandakanya ibele, ikholoni, kunye nomhlaza wesinyi. Nangona kunjalo, kubalulekile ukuqaphela ukuba uninzi lwezi zifundo zenziwe kwi-vitro okanye kwiimodeli zezilwanyana, kwaye izifundo ezininzi zabantu ziyafuneka ukuqinisekisa ezi ziphumo.

Kwindawo yesifo se-cardiovascular disease, amandla e-resveratrol okuphucula umsebenzi we-endothelial (impilo ye-blood vessel lining) ifumene ingqalelo. Uhlalutyo lwe-meta lwezilingo zeklinikhi lufumene ukuba i-resveratrol supplementation iphucule kakhulu i-flow-mediated dilation, umlinganiselo we-endothelial function. Olu phuculo lunokunciphisa umngcipheko wesifo senhliziyo kunye nesifo sohlangothi.

Abaphandi bakwaphanda amandla e-resveratrol ekuthinteleni nasekulawuleni izifo ze-neurodeergenerative. Izifundo zezilwanyana zibonise ukuba i-resveratrol inokunciphisa ukuqokelela kwe-beta-amyloid plaques, uphawu lwesifo se-Alzheimer. Ukongeza, iipropathi zayo ezichasayo kunye ne-antioxidant zinokunceda ukukhusela iiseli zengqondo kumonakalo ohambelana neemeko ezifana nesifo sikaParkinson.

Impembelelo yekhompawundi kwimpilo ye-metabolic yenye indawo yophando olusebenzayo. Izifundo zihlola indlela i-resveratrol enokunceda ngayo ukukhusela okanye ukulawula uhlobo lwe-2 yeswekile ngokuphucula uvakalelo lwe-insulin kunye ne-glucose metabolism. Olunye uphando luye lwabonisa ukuba i-resveratrol inokunceda ukulwa nokutyeba ngokuchaphazela i-fat metabolism kunye nokunciphisa ukuvuvukala kwizicubu ze-adipose.

Ngelixa ezi nkalo zophando zithembisa, kubalulekile ukujongana neziphumo ngononophelo. Izifundo ezininzi zisekwinqanaba labo lokuqala, kwaye ubukhulu becala, izilingo zabantu zexesha elide ziyafuneka ukuze kuqondwe ngokupheleleyo amandla e-resveratrol ekuthinteleni isifo.

Njengoko uphando kwi-resveratrol luqhubeka nokuvela, kuyacaca ukuba le khompawundi ibambe amandla abalulekileyo kwicandelo lezempilo kunye nokuba sempilweni. Ukusuka kwiipropathi zayo zokuchasana nokuguga ukuya kwindima yayo ekuthinteleni izifo, i-resveratrol ibonelela ngendlela enomdla yokuhlola ngakumbi. Nangona uphando olongezelelweyo lufunekayo ukuze uqonde ngokupheleleyo izibonelelo zalo kunye nokusetyenziswa ngokufanelekileyo, ubungqina obukhoyo bubonisa ukuba ukubandakanya ukutya okutyebileyo kwe-resveratrol kukutya okunokulinganisela kunokuba lukhetho olunobulumko kwabo bafuna ukuxhasa impilo yabo yonke.

Khumbula, ngelixa i-resveratrol ibonisa isithembiso, asiyombumbulu yomlingo. Indlela yokuphila enempilo, kubandakanywa nokutya okunokulinganisela, ukuzivocavoca rhoqo, kunye nokulawula uxinzelelo, uhlala usisiseko sempilo enhle. Njengesiqhelo, kubalulekile ukudibana nengcali yezempilo phambi kokuba uqalise nayiphi na irejimeni entsha yokongeza.

Iingxelo:

1. Baur, JA, & Sinclair, DA (2006). Amandla onyango lwe-resveratrol: ubungqina be-vivo. Uphononongo lweNdalo Ukufunyanwa kweziyobisi, 5 (6), 493-506.
2. Bonnefont-Rousselot, D. (2016). Resveratrol kunye nezifo zentliziyo. Izondlo, 8(5), 250.
3. Smoliga, JM, Baur, JA, & Hausenblas, HA (2011). I-Resveratrol kunye nempilo-Uphononongo olubanzi lwezilingo zeklinikhi zabantu. I-Molecular Nutrition & Food Research, 55 (8), 1129-1141.
4. Timmers, S., Auwerx, J., & Schrauwen, P. (2012). Uhambo lwe-resveratrol ukusuka kwigwele ukuya emntwini. Ukuguga, 4(3), 146-158.
5. Walle, T. (2011). I-Bioavailability ye-resveratrol. Iingxelo zeNew York Academy yeSayensi, i-1215 (1), i-9-15.
6. Zordoky, BN, Robertson, IM, & Dyck, JR (2015). Ubungqina bezonyango kunye neklinikhi yendima ye-resveratrol kunyango lwezifo zentliziyo. I-Biochimica et Biophysica Acta (BBA) -Isiseko seMolekyuli yeSifo, i-1852 (6), i-1155-1177.

Ngaba unomdla wokufunda ngakumbi malunga ne-resveratrol kunye nezinye izixhobo zeprimiyamu zokutya kunye nezempilo? Qhagamshelana ne-YANGGE BIOTECH ku-info@yangngebiotech.com ukuze ufumane iingcebiso zeengcali kunye neemveliso ezikumgangatho ophezulu ukuxhasa impilo yakho kunye neenjongo zempilo.