Yintoni iPyrroloquinoline Quinone (PQQ)?

Iprroloquinoline Quinone (PQQ) yimolekyuli encinci enevumba elimnandi efumaneka kukutya okwahlukeneyo nakwimizimba yethu. Iingcali zenzululwazi zihlela i-PQQ njengesondlo esinceda kwimveliso yamandla kunye nokukhuselwa kumonakalo weeseli. Idlala indima ebalulekileyo kulawulo lwamandla omzimba wethu kunye neenkqubo zokhuselo. 

Ngo-1979, usokhemisi waseJapan uTatsuo Sakamoto, ngelixa wayeqhuba uphando olufanayo, wasebenzisa indlela entsha yokukhupha i-PQQ ekutyeni okuvundisiweyo (iviniga emnyama ka-Amami Ōshima). Ngasekupheleni kwee-1980s, kwafunyaniswa ukuba i-PQQ ayisiyonto i-antioxidant kuphela kodwa ikwakhuthaza ukukhula kunye nemetabolism yee-microorganisms kwaye ikhuthaza ukuveliswa kwamandla eseli. Ezi ziphumo zafumana ingqwalasela ebanzi kuluntu lwezenzululwazi.

 

Imisebenzi yebhayoloji yePQQ

Imisebenzi yebhayoloji ye PQQ ikakhulu kugxilwe kwimiba emibini ephambili: okokuqala, isebenza njenge-mitochondrial vitality booster, exhasa ukukhula nophuhliso lwe-mitochondria kunye nokukhuthaza ukukhula okukhawulezayo kweeseli zomntu. Okwesibini, ineepropathi ezigqwesileyo ze-antioxidant, ezinceda ukuphelisa iiradicals zasimahla kunye nokunciphisa umonakalo weseli. Le misebenzi mibini yenza ukuba idlale indima enamandla kwimpilo yengqondo, impilo yentliziyo, kunye nempilo yokusebenza kwemetabolism.

Kwintsimi yokhathalelo lwesikhumba, i-PQQ ineepropathi ezomeleleyo ze-antioxidant ezisusa ngempumelelo ii-radicals zasimahla, zilibazisa ukuguga kolusu, kunye nokukhuthaza ukuveliswa kwe-collagen ukomeleza ukuqina kolusu kunye nokuphucula ukuthambisa kolusu. Ukongeza, ezinye iiphononongo zicebisa ukuba inokukhuthaza ukulungiswa kunye nokuvuselelwa kolusu, kubandakanya ukuphiliswa kwenxeba ngokukhawuleza, ukunciphisa iimpendulo ezivuthayo, kunye nokwandisa amandla okuzilungisa ulusu.

 

IiNzuzo ze-PQQ kwi-Skincare

PQQ inemisebenzi emininzi kunye neenzuzo ezinokubakho kukhathalelo lwesikhumba. Isayensi kwesi sithako isakhula, kodwa okwangoku, ezinye zezona zibonelelo zibalulekileyo zokhathalelo lwe-PQQ zezi:

1. I-Antioxidant enamandla - I-PQQ isebenza njenge-antioxidant enamandla, okuthetha ukuba ikhusela iiseli zakho kumonakalo obangelwa ziiradicals zasimahla. I-radicals yamahhala i-molecule ezingazinzanga ezinokulimaza iiseli, ezikhokelela ekugugeni kunye neengxaki ezahlukeneyo zesikhumba. Ngokuthoba ezi molekyuli ziyingozi, i-PQQ inceda ukugcina ulusu lwakho lukhangeleka lulutsha kwaye lusempilweni. Uphononongo lubonise ukuba i-PQQ inokunciphisa uluhlu olubanzi lweeradicals zasimahla, kubandakanya nezo ziveliswa yimitha ye-UV kunye nongcoliseko.
2. Ukonyusa amandla eSelula - I-PQQ inceda ukwandisa inani le-mitochondria kwiiseli. IMitochondria inoxanduva lokuvelisa amandla (ATP) kwiiseli. I-mitochondria eninzi ithetha amandla amaninzi, anceda iiseli zesikhumba zizilungise ngokukhawuleza kwaye zihlale zisempilweni. Oku kunokubangela ibala eliqaqambileyo nelinempilo. I-PQQ yenza kusebenze iijini ezithile ezikhuthaza i-mitochondrial biogenesis, ekhokelela ekwandeni kwemveliso yamandla ngaphakathi kweeseli zolusu.
3. Yehlisa Ukukrala -Ukudumba kunokubangela ububomvu, ukudumba, nokungakhululeki eluswini. I-PQQ ineempawu ezichasayo ezinceda ekunciphiseni ezi mpawu. I-PQQ inciphisa ukuvuvukala ngokunciphisa amanqanaba eemolekyuli ezikhuthaza ukuvuvukala, njenge-interleukin-6 (IL-6) kunye ne-C-reactive protein (CRP). Oku kwenza kube luncedo kubantu abaneemeko ezifana ne-acne kunye ne-rosacea.
4. Ukuphucula umqobo wesikhumba - Umqobo wesikhumba ufana nodonga olugcina ukufuma kunye nezinto ezinobungozi ngaphandle. I-PQQ yomeleza lo mqobo ngokukhuthaza ukuveliswa kwee-ceramide kunye nezinye iilipids eziyimfuneko ekugcineni umqobo wolusu olusempilweni. Oku kunceda ulusu lwakho luhlale lumanzi kwaye lukhuselwe kumonakalo wokusingqongileyo njengongcoliseko kunye nemitha ye-UV. Ukuphuculwa komsebenzi wokuthintelwa kwesikhumba kunciphisa ukulahleka kwamanzi e-transepidermal (TEWL) kunye nokuphucula ukuhanjiswa kwesikhumba ngokubanzi.

 

PQQ Iziphumo ebezingalindelekanga

Nakuba PQQ ikhuselekile ngokubanzi, abanye abantu banokufumana iziphumo ebezingalindelekanga ezingephi njengokungakhululeki kwesisu okanye intloko ebuhlungu, ngakumbi ukuba bathatha iidosi zomlomo eziphezulu. Ezi ziphumo bezingalindelekanga zinqabile, kodwa ihlala ingumbono olungileyo ukuqala ngexabiso elincinci kwaye ubone ukuba umzimba wakho usabela njani.

Imibutho efana neZiko leSizwe lezeMpilo ikwahlela i-Pyrroloquinoline quinone njengesithako esikhuselekileyo kukhathalelo lwesikhumba.

PQQ izongezo

I-PQQ iyafumaneka kwifomu yokuncedisa kwaye inokuthatyathwa ngomlomo. Uphononongo lubonisa ukuba ukuthatha izongezo ze-PQQ kunokuphucula iimpawu ezahlukeneyo zezempilo, kubandakanya ukunciphisa ukudumba kunye nokunyusa umsebenzi we-mitochondrial. Ngezibonelelo zesikhumba, iidosi eziqhelekileyo zivela kwi-10 ukuya kwi-20 mg ngosuku. Nangona kunjalo, kungcono ukudibana nomboneleli wezempilo ngaphambi kokuba uqale nayiphi na isongezelelo esitsha ukuze uqinisekise ukuba ikulungele.

PQQ vs CoQ10

bobabini PQQ kunye ne-CoQ10 zithandwa ngezibonelelo zabo zolusu, kodwa banomahluko ofihlakeleyo. Lo mahluko ubandakanya:

1. Ulwakhiwo kunye noMsebenzi- I-PQQ inceda ukudala i-mitochondria entsha, ngelixa i-CoQ10 inceda i-mitochondria ekhoyo isebenze ngcono. Cinga nge-PQQ njengokwandisa inani leefektri zamandla kwiiseli zakho, ngelixa i-CoQ10 iphucula ukusebenza kakuhle kweefektri ezikhoyo.
2. Amandla eAntioxidant - Zombini i-PQQ kunye ne-CoQ10 zi-antioxidants ezinamandla. Nangona kunjalo, i-PQQ ihlala iqaqambisa amandla ayo okunciphisa uluhlu olubanzi lweeradicals zasimahla ngempumelelo. I-CoQ10 isemagqabini ekukhuseleni iiseli zolusu kuxinzelelo lwe-oxidative kwaye isetyenziswa kakhulu kukhathalelo lwesikhumba ngezibonelelo zayo eziqinisekisiweyo.
3. Inkxaso yeMitochondrial - Ngelixa zombini i-PQQ kunye ne-CoQ10 zixhasa impilo ye-mitochondrial, ukukwazi kwe-PQQ ukwenza i-mitochondria entsha inika umda ekwandiseni amandla eselula ngokubanzi. Oku kwanda kwemveliso yamandla kunceda iiseli zesikhumba zihlale zisempilweni kwaye zizilungise ngokufanelekileyo.
4. IiNzuzo zizonke - Zombini i-PQQ kunye ne-CoQ10 inokuphucula impilo yolusu. Ipropathi ye-PQQ ye-antioxidant kunye ne-anti-ukudumba iyenza isebenze ekukhuseleni ukonakaliswa kwendalo kunye nokuthomalalisa ulusu olunomsindo. I-CoQ10 yaziwa kakhulu ngokugcina i-collagen yesikhumba kunye nokunciphisa ukubonakala kwemigca emihle kunye nemibimbi ngokuxhasa ukuveliswa kwamandla kwiiseli zesikhumba.

Zeziphi iintlobo zolusu ezinokusebenzisa i-PQQ?

I-Baumann Skin Typing System ihlela ulusu kwiindidi ezili-16 ezahlukeneyo ngokusekelwe kumsebenzi wokuthintela ulusu, uvakalelo, ukuguga, kunye nebala. Nanku umntu onokuzuza kakhulu kubo PQQ:

1. Iintlobo zolusu olomileyo - Ngokuncedisa ekudibaneni kwee-lipids ezibalulekileyo njengeeceramides, esi sithako sinokunceda iintlobo zolusu ezomileyo zibambelele kubumanzi esele bulusu lwabo.
2. Iintlobo zolusu olubuthathaka - Ekubeni esi sithako sivala iindlela ezithile zokudumba, lukhetho olulungileyo njengesithako esithomalalisayo, esichasene nokudumba kwiintlobo zolusu ezibuthathaka.
3. Imibimbi Iintlobo zolusu -Iintlobo zolusu ezithanda ukushwabana zinokuzuza kwi-antioxidant kunye neepropathi ezikhuthaza iiseli ze-PQQ. Nangona ingayi kumisa ukuguga, inokudlala indima exhasayo kwirejimeni yokuchasana nokuguga.​​​​​​​

 

isiphelo

IPrroloquinoline Quinone (PQQ) sisithako esiphawulekayo esinoluhlu olubanzi lweenzuzo zokunakekelwa kwesikhumba. Ukusuka kwipropathi yayo enamandla ye-antioxidant kunye ne-anti-ukudumba ukuya kubuchule bayo obukhethekileyo bokuxhasa impilo ye-mitochondrial, i-PQQ inokuphucula kakhulu impilo kunye nenkangeleko yolusu. Nokuba unolusu olomileyo, olubuthathaka, okanye olulupheleyo, i-PQQ inokuba sisithako esenza umahluko obonakalayo kwindlela yakho. Ngalo lonke ixesha ukhumbule ukudibana nomboneleli wezempilo ngaphambi kokuba uqalise nasiphi na isongezelelo esitsha kwaye ucinge ngokuthatha i-quiz ye-Baumann Skin Type ukuze ufumanise ukuba i-PQQ ifanelekile kwiimfuno ezithile zolusu lwakho.