IiNzuzo zoMbane weNgonyama kwiMpilo yeBrain

Ngaba ujonge ukukhulisa ingqondo enamandla kunye nomzimba onamandla ngakumbi? Impendulo isenokuba kwikhowa elityiwayo nelinonyango elibizwa ngokuba yiLion's Mane powder (Hericium erinaceus). Eli khowa livela kwiindawo ezininzi kumhlaba osemantla kuquka uMntla Melika, iYurophu, iTshayina, neJapan, kwaye eli khowa libukeka lingaqhelekanga lifumene indlela yokungena kwibhokisi yethu yezixhobo zonyango njengeyeza leemeko ezahlukeneyo kunye nenkxaso yomzimba ophilileyo, ingqondo ephilileyo, kunye neemvakalelo eziphilileyo.

Yintoni i-Lion's Mane Mushroom kwaye zithini iMisebenzi yayo?

Umgubo weLion's Mane (Hericum Erinaceus), okwaziwa ngokuba yiHou Tou Gu, ngamakhowa amakhulu, amhlophe, nanezimbotshana ezifana nomnqwazi wengonyama. Kangangeenkulungwane ebesetyenziswa kwizityalo zaseJapan ngokuwenza iti kwaye asetyenziswe njenge-tonic.

I-Lion's mane mushroom extract inyusa i-nerve growth factor (NGF), inceda ekulungiseni, ekulondolozeni, nasekuvuseleleni izicubu ze-neuron kunye nobuchopho. Ingaphucula inkumbulo kunye nokugxila ngelixa ixhasa ukusebenza kwengqondo kunye nenkqubo ye-nervous. Iqulethe amanqanaba aphezulu e-beta-glucans (25% nangaphezulu) aziwa ngeempawu zawo zokuxhasa amajoni omzimba, kunye nee-antioxidants zokukhusela iiseli, kunye nokwandisa amandla.

 

 

Izondlo eziphambili kwi-Lion's Mane

 

Phambi kokuntywila kwiinzuzo zengqondo, kuyanceda ukuqonda ukuba yintoni eyenza i-Lion's Mane ibe namandla. Ityebile kwi:

• IiHericenones (ezifumaneka emzimbeni ovelisa iziqhamo) – Zikhuthaza ukwenziwa kwe-NGF.

• Ii-Erinacines (ezifumaneka kwi-mycelium) – Ziphucula i-NGF kumqobo wegazi-ubuchopho.

• IiPolysaccharides - Ixhasa ukusebenza komzimba kwaye inciphisa ukudumba.

• IiBeta-glucans – Zibonelela ngeempawu ze-antioxidant kunye ne-neuroprotective.

• I-Ergothioneine – I-amino acid engaqhelekanga ye-antioxidant enefuthe lokukhusela i-cytoprotective.

Ngokudibeneyo, ezi khompawundi zenza i-Lion's Mane ibe sisixhobo esinamandla sempilo yobuchopho kunye nokhuseleko lwengqondo.

 

 

IiMushrooms zeNgonyama yeMpilo yeBrain

 

Kuyacaca ukuba imisebenzi yobuchopho ngokwemvelo iyancipha ngokuhamba kwexesha. Iimpawu ezinxulumene nokuguga ezinjengokuncipha kwengqondo, ukulahleka kwenkumbulo, kunye nokungabikho kokugxila kuye kwadityaniswa nezinto ezinje ngokuncipha kwee-neurons kunye neeseli zobuchopho ezonakeleyo. 

Uphando lubonisa ukuba i-Lion's mane mushroom inamandla okukhuthaza impilo yengqondo ngokuvuselela ukudalwa kweNerve growth factor (NGF) kunye ne-Brain-derived neurotrophic factor (BDNF).

I-NGF kunye ne-BDNF ziiprotheni ezikhuthaza ukuveliswa kweeseli ezintsha kunye nokuqinisa esele zikhona. I-NGF ikwabalulekile ekwenziweni kwe-myelin, isigqubuthelo esijikeleze iiseli zemithambo-luvo enceda ukuhambisa iimpembelelo ezivuselela iiseli zengqondo ukuba zenze umsebenzi wazo. I-BDNF yandisa ukunyameka kwengqondo, inceda iiseli zengqondo ukuba zigcine ingqibelelo yazo.

Kucingelwa ukuba negalelo kwimpilo yethu ubuncinane ngeendlela ezintathu:

Isebenza Njenge-Antioxidant – Kwiimvavanyo ezikwinqanaba leeseli, i-Lion's Mane ibonakalise amandla abalaseleyo e-antioxidant.

Ukuphucula iMicrobiome – Ubungqina bokuqala bubonisa ukuba iLion's Mane inokuba negalelo kulwahlulo lwe-microbiome yamathumbu kunye nempilo yamathumbu iyonke ngefuthe le-prebiotic kwiintsholongwane zamathumbu ngelixa izifundo kwinqanaba leeseli zibonisa ukuba zinamandla okucinezela iintsholongwane ezingaphiliyo.

Iiseli zobuchopho ezondlayo – Iikhompawundi ezithathwe kwiLions' Mane zibonakaliswe kwinqanaba leeseli ukukhuthaza ukuveliswa kwe-NGF (i-nerve growth factor), ikhompawundi ebalulekileyo kwii-neurons ezisempilweni, ngelixa zikwanokunciphisa ukudumba kweeseli zobuchopho ngokubanzi.

 Ngelixa ezi ziphumo zinika umdla kwaye zithembisayo, owona mdla wam usoloko ulele ekubeni ngaba sele ziguqulelwe kwizifundo zabantu - ke masiyiphonononge ngokulandelayo.

 

Ukunciphisa iimpawu ze-Neuro-Degeneration

Ngo-2008, i-double blind-blind, i-parallel-group, i-placebo-controlled controlled trial trial yafumanisa ukuba i-lion's mane iphucule ngempumelelo umsebenzi wokuqonda kwiqela elingenamkhethe labantu abadala be-15. Izifundo ze-rodent zafumanisa ukuba ikhowa inokukhusela kwimiphumo ye-Parkinson kunye ne-Alzheimer's disease, kuquka ukunyakaza okuzenzekelayo kunye nokulahlekelwa kwememori. 

Kudliwanondlebe lukaJoe Rogan's podcast, i-mushroom guru kunye nomseki we-Host Defense uPaul Stamets wathi i-lion mane mushroom "inceda ukuphelisa i-amyloid plaque kunye nokuvuselela i-myelin sheaths."

 I-Amyloid plaque yiprotheni ene-acidic edityaniswe nokutshatyalaliswa kweeseli kunye nokuchithwa kwezicubu. Ukuqhekeka kwe-Myelin licandelo eliphambili elinegalelo kwiimpawu ze-Parkinson kunye ne-Alzheimer's disease.

 

Uwuthatha njani umnwe weNgonyama kwiMpilo yeBrain

I-Lion's Mane ifumaneka ngeendlela ezahlukeneyo:

• Umgubo (umzimba owomileyo okanye i-mycelium)

• Iipilisi

• Iinkcenkce

• Iitshomi

• Iti ephuhliweyo okanye i-coffee blends

Umthamo ocetyiswayo:

• Inkxaso ngokubanzi yengqondo : 500–1000 mg/ngosuku

• Inkxaso yonyango okanye yokuvuselela imithambo-luvo : Ukuya kuthi ga kwi-3000 mg/ngosuku (phantsi kwesikhokelo)

Icebiso: Khetha i-Lion's Mane ekhutshwe kabini (ekhupha amanzi kunye notywala) ukuqinisekisa ukuba ufumana uluhlu olupheleleyo lweekhompawundi ezisebenzayo—ii-hericenones kunye nee-erinacines.

 

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Ukhuseleko kunye nemiphumo emibi

Umgubo weLion's Mane uhlala unyamezelwa kwaye ukhuselekile kubantu abaninzi. Nangona kunjalo:

• Ukunganyamezelani kakuhle kokugaya ukutya okanye ukurhawuzelela kolusu kunokwenzeka kubantu abanobuthathaka.

• Kungcono ukubonisana nomboneleli wakho wezempilo ngaphambi kokuba usebenzise ukuba ukhulelwe , uncancisa , okanye usela amayeza esifo seswekile okanye uxinzelelo lwegazi.

isiphelo

I-Lion's Mane mushroom extract ivelele njengenye yezona zinto zinamandla zemvelo ezixhasa impilo yengqondo, inika indibaniselwano eyahlukileyo yeenzuzo zengqondo, iimvakalelo, kunye nokukhusela imithambo-luvo. Ukusuka ekukhuthazeni ukukhula kwemithambo-luvo (NGF) ukuya ekuxhaseni inkumbulo, ukugxila, kunye nokuphila kakuhle ngokweemvakalelo, impembelelo yayo ixhaswa ngokwesayensi kwaye ivavanywa ixesha elide kwiinkulungwane zokusetyenziswa kwendabuko. Nokuba ujonge ukuphucula ukusebenza kwengqondo yemihla ngemihla, ukukhusela ekuwohlokeni kwengqondo okunxulumene nobudala, okanye ukuxhasa ukubuyela kwimeko yesiqhelo kuxinzelelo lwengqondo, ukufaka iLion's Mane kwinkqubo yakho yokuphila kakuhle lukhetho olukrelekrele nolwendalo. Ngeprofayili yayo yokhuseleko oluhle kunye nophando olukhulayo, iLion's Mane ingaphezulu nje kwesongezo-lutyalo-mali olusebenzayo kwimpilo yengqondo yakho yexesha elide kunye namandla.

Ucaphulo

1. Mori, K., Inatomi, S., Ouchi, K., & Tuchida, T. (2009). Ukuphucula imiphumo ye-mushroom i-Yamabushitake (i-Hericium Erinaceus) kwi-mild impairment yengqondo: uvavanyo lwekliniki olulawulwa yi-placebo oluyimfama kabini. Mar;23(3):367-72. doi: 10.1002/ptr.2634. Ifunyenwe kwi https://www.ncbi.nlm.nih.gov/pubmed/18844328?dopt=Abstract
2. Chiu C,H., Chyau C,C., Chen C,C., Lee L,Y., Chen W,P.,Liu J,L.,Lin W,H.,Mong M,C. (2018). I-Erinacine A-Enriched Hericium erinaceus Mycelium Ivelisa i-Antidepressant-Effects efana ne-Modulating BDNF/PI3K/Akt/GSK-3β Ukubonakaliswa kwiiMice. Ijenali yaMazwe ngaMazwe yeNzululwazi yeMolekyuli. Januwari 24;19(2). ipii: E341. doi: 10.3390/ijms19020341. Ifunyenwe kwi https://www.ncbi.nlm.nih.gov/pubmed/29364170
3. Ryu S., Kim H,G., Kim J,Y., Kim S,Y., Cho K,O. (2018). I-Hericium erinaceus Extract iNciphisa ukuxhalaba kunye nokuziphatha okuxinzelelekileyo ngokuKhuthaza i-Hippocampal Neurogenesis kwi-Brain ye-Adult Mouse. Ijenali yokutya koNyango. Feb;21(2):174-180. doi: 10.1089/jmf.2017.4006. Ifunyenwe kwi  https://www.ncbi.nlm.nih.gov/pubmed/29091526
4. Liu J., DU C., Wang Y., Yu Z. (2015). Imisebenzi yokulwa nokukhathala kwe-polysaccharides ekhutshwe kwi-Hericium erinaceus. Iyeza loMfuniselo kunye noNyango. Feb;9(2):483-487. Ifunyenwe kwi  https://www.ncbi.nlm.nih.gov/pubmed/25574220?dopt=Abstract
5. Yang Y., Zhao C., Diao M., Zhong S., Sun M., Sun B., Ye H., Zhang T. (2018). Umsebenzi we-Prebiotic we-Simulated Gastric kunye ne-Intestinal Digesta ye-Polysaccharides esuka kwi-Hericium erinaceus. Iimolekyuli. Nov 30;23(12). ipii: E3158. doi: 10.3390/molecules23123158. Ifunyenwe kwi https://www.ncbi.nlm.nih.gov/pubmed/30513668